Despite advancements, several challenges persist in precision measurement at the nanoscale:
Sample Preparation: Preparing samples without altering their inherent properties is difficult and time-consuming. Environmental Factors: Variations in temperature, humidity, and vibrations can affect measurement accuracy. Instrument Calibration: Regular calibration of instruments is essential to maintain accuracy, which can be challenging due to the sensitivity of the equipment. Data Interpretation: Analyzing and interpreting data from these advanced techniques requires specialized knowledge and expertise.