What Challenges Exist in Implementing SPAAC in Nanotechnology?
Despite its advantages, implementing SPAAC in nanotechnology faces some challenges:
Scalability: Producing large quantities of strained alkynes can be costly and technically challenging. Stability: Some strained alkynes may be less stable and prone to side reactions, which might affect the overall efficiency and specificity of the reaction. Optimization: Specific reaction conditions may need to be optimized for different nanomaterials and biological systems to achieve the best results.
