strain promoted azide alkyne cycloaddition (spaac)

What Are the Advantages of Using SPAAC in Nanotechnology?

Using SPAAC in nanotechnology offers several advantages:
Bioorthogonality: The reaction occurs without interfering with natural biological processes, making it ideal for in vivo applications.
High Efficiency: SPAAC reactions are rapid and yield high product purity, which is essential for consistent nanomaterial performance.
Mild Conditions: The reaction can be carried out under physiological conditions, preserving the functionality of sensitive biomolecules and nanomaterials.
Versatility: SPAAC can be applied to a wide range of substrates, including proteins, nucleic acids, and synthetic polymers.

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