Several strategies can be employed to mitigate channel clogging:
1. Surface Modification: Coating channel walls with hydrophilic or hydrophobic materials can reduce the adhesion of particles and biological entities. 2. Optimized Flow Conditions: Adjusting flow rates and using pulsatile flows can prevent the accumulation of particles. 3. Chemical Treatments: Introducing anti-fouling chemicals or surfactants can help in maintaining open channels. 4. Regular Maintenance: Periodic cleaning and flushing of channels can prevent clogging.