What are the Challenges of Using PEG in Nanotechnology?
Despite its advantages, there are several challenges associated with the use of PEG in nanotechnology:
Immune Response: Repeated exposure to PEG can lead to the development of anti-PEG antibodies, potentially reducing the efficacy of PEGylated nanomedicines. Degradation: PEG can degrade under certain physiological conditions, which may affect the stability and performance of PEGylated nanoparticles. Regulatory Issues: The regulatory landscape for PEGylated nanomaterials is complex and requires thorough evaluation for safety and efficacy.