Several factors can contribute to channel clogging in nanotechnology:
1. Particle Aggregation: Nanoparticles may aggregate due to various forces such as van der Waals forces or electrostatic interactions, leading to blockages. 2. Chemical Precipitation: Chemical reactions within the channels can result in the formation of insoluble compounds that clog the pathways. 3. Biological Fouling: In biological applications, microorganisms, proteins, or cells can adhere to channel walls and cause blockages. 4. Physical Obstruction: Physical debris or contaminants introduced during the manufacturing or operational phases can obstruct channels.