Understanding immune reactions to nanoparticles is crucial for several reasons:
1. Safety: Ensuring that nanoparticles do not trigger harmful immune reactions is essential for patient safety. 2. Efficacy: Immune clearance of nanoparticles can reduce their therapeutic effectiveness. 3. Regulatory Approval: Understanding and mitigating immune reactions are critical for gaining regulatory approval for nanomedicines. 4. Clinical Translation: Successful translation of nanotechnology from the lab to the clinic requires a comprehensive understanding of immune interactions.
