Thiol groups are crucial in nanotechnology for several reasons:
Surface Functionalization: Thiol groups can readily form covalent bonds with metal surfaces, such as gold and silver, making them ideal for surface functionalization of nanoparticles and nanomaterials. Self-Assembled Monolayers: They facilitate the creation of SAMs, which are organized layers of molecules spontaneously assembled on surfaces. These layers can modify surface properties such as hydrophobicity, conductivity, and reactivity. Biocompatibility: Thiol-modified nanoparticles are often used in biomedical applications due to their ability to easily conjugate with biomolecules, enhancing their biocompatibility and functionality in biological systems.
