Zwitterionic coatings are unique surface modifications that contain both positive and negative charges within the same molecule. These coatings are highly effective in resisting biofouling, which is the undesirable accumulation of microorganisms, algae, and proteins on surfaces. In the context of nanotechnology, zwitterionic coatings are used to improve the performance and longevity of nanomaterials by enhancing their biocompatibility and stability.