What Materials Are Used for siRNA Loaded Nanoparticles?
Several types of materials are used to create these nanoparticles: - Lipid-based nanoparticles: Lipid nanoparticles, such as liposomes, are commonly used due to their biocompatibility and efficiency in encapsulating nucleic acids. - Polymeric nanoparticles: Polymers like PLGA (poly(lactic-co-glycolic acid)) offer controlled release properties and are biodegradable. - Inorganic nanoparticles: Materials like gold and silica nanoparticles are employed for their unique physical and chemical properties, including ease of functionalization. - Dendrimers: These are branched polymers that offer a high degree of functionalization and encapsulation efficiency.
