The biotin-streptavidin system is a widely used molecular interaction in biotechnology and nanotechnology. Biotin, also known as vitamin B7, is a small molecule that can be easily conjugated to proteins, nucleic acids, and other biomolecules. Streptavidin is a protein derived from the bacterium Streptomyces avidinii and has an extremely high affinity for biotin. The binding affinity between biotin and streptavidin is one of the strongest non-covalent interactions known in nature, making it an ideal tool for various applications in nanotechnology.
