How is the Biotin-Streptavidin System Used in Biosensors?
In biosensors, the biotin-streptavidin system is employed to immobilize biomolecules such as enzymes, antibodies, or DNA on sensor surfaces. For example, a biotinylated antibody can be immobilized on a streptavidin-coated sensor surface to create a highly specific detection platform. When a target analyte binds to the antibody, changes in the sensor's properties (such as electrical resistance or fluorescence) can be measured, enabling the detection of the analyte with high sensitivity and specificity.
