What are the Limitations of the Micronucleus Test?
1. False Positives/Negatives: There is a risk of false results due to factors such as culture conditions and staining techniques. 2. Limited Mechanistic Insights: While the test indicates genotoxicity, it does not provide detailed information about the underlying mechanisms of damage. 3. Standardization Issues: Variations in protocols can lead to inconsistencies in results, necessitating stringent standardization.
