The key parameters measured in toxicological tests include:
- Cytotoxicity: The ability of nanoparticles to cause cell death or damage. - Genotoxicity: The potential of nanoparticles to induce genetic mutations or DNA damage. - Oxidative Stress: The production of reactive oxygen species (ROS) by nanoparticles, leading to cellular damage. - Inflammation: The induction of an inflammatory response by nanoparticles. - Biodistribution: The distribution and accumulation of nanoparticles in different tissues and organs. - Bioaccumulation: The accumulation of nanoparticles in organisms over time.
