What are the Consequences of Denaturation in Nanomedicine?
In nanomedicine, denaturation can have several consequences:
- Loss of Function: Therapeutic proteins or enzymes that denature lose their biological activity, rendering them ineffective. - Immunogenicity: Denatured proteins may expose hidden epitopes, triggering an immune response. - Aggregation: Denatured proteins can aggregate, potentially leading to adverse effects such as immunogenic reactions or toxicity.
