To prevent or mitigate denaturation in nanotechnology applications, several strategies can be employed:
- Surface Modification: Coating nanomaterials with biocompatible polymers or ligands can reduce denaturation by minimizing direct contact with biological molecules. - Controlled Environment: Maintaining optimal conditions such as pH and temperature during the interaction of nanomaterials with proteins can help preserve their native structures. - Stabilizers: Adding stabilizing agents like glycerol or trehalose can protect proteins from denaturation during storage and application.
