What are the challenges in studying in vivo behavior of nanoparticles?
Studying the in vivo behavior of nanoparticles presents several challenges:
1. Complexity of biological systems: The dynamic and complex nature of living organisms makes it difficult to predict how nanoparticles will behave. 2. Variability: Differences in animal models, administration routes, and experimental conditions can lead to inconsistent results. 3. Detection and quantification: Measuring the concentration and distribution of nanoparticles in tissues requires sensitive and specific analytical techniques, such as mass spectrometry and imaging methods.
