What Are the Challenges in Studying Clearance Mechanisms?
Studying clearance mechanisms entails several challenges:
Complexity of Biological Systems: The human body is highly complex, and simulating its conditions in a laboratory setting is difficult. Variability in Nanoparticle Properties: Even slight changes in nanoparticle properties can significantly affect their behavior and clearance. Long-Term Effects: Long-term studies are needed to understand the potential accumulation and chronic effects of nanoparticles. Interindividual Variability: Differences in genetics, health status, and environmental exposure among individuals can lead to variable clearance rates.
