What are the Challenges in Achieving High Targeting Efficiency?
Despite advancements, achieving high targeting efficiency remains challenging due to:
Biological Barriers: The bodyâs immune system can recognize and eliminate foreign particles. Non-Specific Binding: Nanoparticles might bind to unintended sites. Heterogeneity of Tumor Cells: Variability in receptor expression among tumor cells can affect targeting. Complex Biological Environment: The dynamic and complex nature of biological systems can impact nanoparticle behavior.
