Several factors affect the targeting efficiency of nanoparticles:
Particle Size: Smaller nanoparticles can navigate through biological barriers more easily. Surface Modification: Functionalizing the surface with ligands or antibodies can enhance specificity. Shape: The shape of nanoparticles can influence their circulation time and uptake by cells. Charge: Surface charge affects interactions with biological membranes. Hydrophobicity/Hydrophilicity: Balancing these properties can improve stability and bioavailability.
