In the realm of Nanotechnology, EMSA has significant applications. Nanotechnology often involves the manipulation and study of biological molecules at the nanoscale. Understanding protein-nucleic acid interactions at this level is crucial for fields such as nanomedicine, nanobiotechnology, and nanoelectronics. For instance, EMSA can be employed to investigate how nanoparticles influence DNA-protein complexes or how they can be used to deliver drugs targeting specific genes.