The absorption of drugs can be significantly enhanced by the use of nanoparticles. These tiny particles can improve the solubility and stability of drugs, leading to better bioavailability. Nanoparticles can be engineered to bypass biological barriers, such as the gastrointestinal tract, which is often a major hurdle for oral drug delivery. For instance, lipid-based nanoparticles can encapsulate hydrophobic drugs and facilitate their transport across the intestinal lining.