Nanoparticles can influence the metabolism of drugs by protecting them from premature degradation. Drugs encapsulated within nanoparticles are often shielded from enzymatic activity, thereby prolonging their half-life and enhancing their therapeutic effect. Additionally, nanoparticles can be designed to release their drug payload in a controlled manner, allowing for sustained drug levels in the bloodstream. This can be particularly beneficial for drugs with a short half-life or those that require precise dosing.