The interaction with nanoparticles can lead to changes in the conformation, function, and stability of proteins. For instance: 1. Structural Changes: Proteins may undergo conformational changes upon binding to nanoparticles, potentially altering their activity. 2. Enzyme Activity: The catalytic activity of enzymes can be either inhibited or enhanced when they interact with nanoparticles. 3. Protein Aggregation: Nanoparticles can induce or inhibit protein aggregation, which is significant in the context of diseases like Alzheimer's.