How Do Charged Nanoparticles Interact with Biological Systems?
Charged nanoparticles interact with biological systems in intricate ways. Positively charged nanoparticles often show increased cellular uptake due to electrostatic attraction with the negatively charged cell membranes. However, this can also lead to higher toxicity. Conversely, negatively charged nanoparticles may exhibit reduced cellular uptake but lower toxicity. Understanding these interactions is essential for designing nanoparticles for biomedical applications, ensuring efficacy while minimizing adverse effects.
