How Can Nanotechnology Help Combat Drug-Resistant Tuberculosis?
Multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) are significant public health challenges. Nanotechnology provides a novel approach to overcome drug resistance by delivering siRNA or CRISPR-Cas9 systems to target and silence resistance genes in TB bacteria. Moreover, nanoparticles can be designed to carry multiple drugs, ensuring a synergistic attack on the bacteria and reducing the likelihood of resistance development.
