Clinical data is essential for several reasons: 1. Validation of Treatments: It helps in validating the effectiveness and safety of nanotechnology-based treatments. 2. Regulatory Approval: Regulatory bodies like the FDA and EMA rely on clinical data to approve new nanomedicines. 3. Risk Assessment: It aids in assessing potential risks associated with nanomaterials, crucial for public health. 4. Guidelines and Protocols: It provides the foundation for developing clinical guidelines and treatment protocols.