Electrochemical nanotransducers operate by facilitating a chemical reaction on the surface of nanostructured electrodes. This reaction generates an electrical signal that can be measured and analyzed. The sensitivity of these devices is significantly enhanced by the large surface area and high reactivity of nanomaterials like carbon nanotubes, metal nanoparticles, and graphene. These materials provide numerous active sites for the chemical reactions to occur, thus amplifying the resulting electrical signal.