The Rodent Bone Marrow Micronucleus Test is a standard genotoxicity assay that detects the formation of micronuclei in the bone marrow cells of rodents. Micronuclei are small, extranuclear bodies that form when chromosome fragments or whole chromosomes fail to incorporate into the daughter nuclei during cell division. The presence of micronuclei indicates chromosomal damage, which can be a precursor to cancer.
