What is Correlative Light and Electron Microscopy (CLEM)?
Correlative Light and Electron Microscopy (CLEM) is an advanced imaging technique that combines the strengths of both light microscopy and electron microscopy. Light microscopy allows for live-cell imaging and the observation of fluorescent tags, while electron microscopy provides high-resolution imaging of cellular structures. By integrating these two methods, CLEM offers a comprehensive view of the nanostructures within biological samples.