Clogging of capillaries can occur due to several reasons:
Aggregation of nanoparticles: When nanoparticles clump together, they form larger particles that can obstruct capillaries. Surface properties: The surface charge, hydrophobicity, and functionalization of nanoparticles can affect their interaction with blood components, potentially leading to clogging. Size and shape: Nanoparticles that are too large or have irregular shapes are more likely to cause blockages.
