What Are the Strategies to Mitigate Nanomaterial-Induced Genomic Instability?
To mitigate the potential genotoxic effects of nanomaterials, several strategies can be employed. One approach is to modify the surface properties of nanomaterials to reduce their reactivity and potential to generate ROS. Another strategy involves the use of antioxidants to neutralize ROS and reduce oxidative stress. Additionally, careful nanomaterial design to avoid direct interactions with DNA and the cellular machinery can help preserve genomic stability. Finally, rigorous safety assessments and regulatory frameworks are essential to ensure the safe application of nanomaterials in biomedicine.
