What Are the Mechanisms of DNA Damage Induced by Nanomaterials?
There are several mechanisms through which nanomaterials can induce DNA damage. One primary mechanism is the generation of ROS, which can result in oxidative stress and subsequent DNA strand breaks. Another mechanism involves the direct interaction of nanomaterials with DNA, leading to physical disruptions in the DNA structure. Lastly, nanomaterials can also interfere with the function of proteins involved in the DNA repair process, compromising the cell's ability to maintain genomic stability.
