What are the Challenges in Uptake and Localization Studies?
Several challenges can complicate these studies: 1. Nanoparticle Characterization: Ensuring consistent size, shape, and surface properties of nanoparticles. 2. Biological Complexity: Accounting for the variability in biological systems, such as differences in cell types and tissue environments. 3. Interference: Minimizing interference from biological fluids and tissues that can affect the accuracy of measurement techniques. 4. Ethical Considerations: Addressing the ethical implications of using animal models and ensuring biocompatibility.