What are the Challenges in Developing Nanofluidic Devices?
Despite their potential, several challenges need to be addressed:
1. Fabrication: Creating nanometer-scale channels with precise dimensions and properties is complex and often costly. 2. Surface Interactions: At the nanoscale, surface interactions dominate, which can lead to issues like clogging or altered fluid behavior. 3. Material Selection: Choosing materials that are compatible with the fluids and biological entities being studied is crucial. 4. Scalability: Scaling up production while maintaining device performance remains a significant hurdle.