What are the Challenges in Biocompatible Modifications?
Complexity of Biological Systems One of the main challenges is the inherent complexity of biological systems. The interaction between nanomaterials and biological tissues can vary significantly based on factors such as size, shape, surface charge, and the presence of specific biomolecules.
Standardization There is a lack of standardized protocols for evaluating the biocompatibility of nanomaterials. This makes it difficult to compare results across different studies and hampers the development of universally accepted biocompatible nanomaterials.
Long-term Effects The long-term effects of nanomaterials in biological systems are still not fully understood. While short-term studies may show biocompatibility, the potential for long-term toxicity or adverse effects remains a concern.