What are the Challenges Associated with PLGA Nanoparticles?
Despite their advantages, PLGA nanoparticles also face several challenges, including:
Stability: Ensuring the stability of the encapsulated drug during storage and after administration is crucial. Scale-Up: Developing reliable and reproducible methods for large-scale production of PLGA nanoparticles can be challenging. Controlled Release: Achieving precise control over the drug release profile can be difficult, particularly for hydrophilic drugs. Immune Response: Understanding and mitigating potential immune responses to PLGA nanoparticles is essential for their safe use in humans.
