Cryo-EM offers several advantages: - High Resolution: It can achieve near-atomic resolution, which is essential for detailed structural analysis. - Preservation of Native State: Samples are preserved in their natural state without the need for fixation or staining, reducing artifacts. - Versatility: It can be used to study a wide range of samples, from proteins and viruses to inorganic nanoparticles and complex nanomaterials. - Time Efficiency: Advances in automation and image processing have significantly reduced the time required to obtain high-resolution structures.
