The administration of PTT involves several key steps:
- Injection of Nanoparticles: The patient receives an injection of specially designed nanoparticles, which accumulate in the tumor due to the enhanced permeability and retention (EPR) effect.
- Laser Irradiation: A laser emitting light at a specific wavelength (usually in the NIR range) is directed at the tumor site. The nanoparticles absorb this light and convert it into heat.
- Heat Generation: The localized heating effect raises the temperature of the tumor cells, leading to their destruction through processes such as protein denaturation and membrane disruption.
