What are the Key Factors Influencing Nanotoxicity?
The toxicity of nanomaterials can be influenced by several factors, including:
Size: Smaller particles have a larger surface area-to-volume ratio, which can increase reactivity and potential toxicity. Shape: The shape of nanomaterials (e.g., rods, spheres, tubes) can affect their interaction with cells and tissues. Surface Chemistry: The presence of surface coatings or functional groups can alter the biological activity of nanomaterials. Aggregation State: Nanoparticles may agglomerate or aggregate, which can influence their distribution and toxicity. Dose: The concentration and duration of exposure to nanomaterials play a critical role in determining toxicity.