Preventing agglomeration is critical for maintaining the unique properties of nanoparticles. Here are several strategies: 1. Surface Modification: Coating nanoparticles with polymers, surfactants, or other molecules can create steric or electrostatic barriers to prevent agglomeration. 2. Optimizing Synthesis Conditions: Controlling parameters like pH, temperature, and ionic strength during nanoparticle synthesis can reduce agglomeration. 3. Using Dispersants: Adding chemicals that can stabilize nanoparticles in a solution can help prevent agglomeration. 4. Mechanical Methods: Ultrasonication and high-shear mixing can break up agglomerates.