Stealth properties are generally achieved through surface modification of nanoparticles. One common method is the attachment of hydrophilic polymers like PEG (Polyethylene Glycol) to the surface of the nanoparticles. This creates a hydration layer around the nanoparticles, preventing protein adsorption and recognition by the immune system. Other methods include the use of zwitterionic polymers and biomimetic coatings that mimic the natural cell membranes.
