The safety of nano enabled sunscreens has been a topic of extensive research and debate. Studies have shown that nanoparticles of ZnO and TiO2 do not penetrate healthy skin beyond the outermost dead layer, the stratum corneum. This suggests that they do not reach viable skin cells or enter the bloodstream, making them safe for topical use. Regulatory agencies like the FDA and European Commission have deemed these nanoparticles safe for use in sunscreens. However, ongoing research continues to monitor and evaluate their long-term safety.