In [nanotechnology], the scale at which materials and devices operate is incredibly small, often at the [nanoscale]. At this scale, even the tiniest particulate contaminant can cause significant issues. For example, in [nanoelectronics], a single contaminant particle can short-circuit a device, leading to failure. In [nanomedicine], contaminants can alter the behavior of [nanodrugs], affecting their efficacy and safety.