What Types of Studies are Conducted in the Preclinical Phase?
Several types of studies are typically conducted during the preclinical phase:
In vitro studies: These involve testing the nanomaterial on cell cultures to evaluate its cytotoxicity, interaction with cellular components, and biological activity. In vivo studies: These involve testing the nanomaterial in animal models to study its biodistribution, metabolism, and long-term effects on living organisms. Mechanistic studies: These explore the underlying mechanisms of action, such as how the nanomaterial affects cellular pathways or immune responses.
