Preclinical studies are the initial phase of research conducted to test the safety, efficacy, and biological activity of nanomaterials and nanodevices before they are used in humans. These studies are crucial as they provide foundational data that inform the design of clinical trials. Typically, preclinical studies involve in vitro and in vivo experiments using cell cultures and animal models. They assess parameters like toxicity, biodistribution, and pharmacokinetics.
