What Methods Are Used for Toxicological Testing of Nanomaterials?
Various methods are employed to assess the toxicity of nanomaterials:
1. In vitro testing: These tests involve studying the effects of nanoparticles on cultured cells. Techniques like cytotoxicity assays, oxidative stress measurements, and genotoxicity tests are commonly used. 2. In vivo testing: Animal models are used to study the systemic effects of nanoparticles, including their distribution, metabolism, and excretion. This helps in understanding potential impacts on different organs and tissues. 3. Computational modeling: Predictive models and simulations can help in understanding the behavior of nanoparticles in biological systems and predicting potential toxic effects.
