What is the Inverse Electron Demand Diels-Alder (IEDDA) Reaction?
The Inverse Electron Demand Diels-Alder (IEDDA) reaction is a type of cycloaddition reaction where an electron-deficient diene reacts with an electron-rich dienophile. Unlike the traditional Diels-Alder reaction, the IEDDA reaction involves a reversal in the electron demand, enabling the formation of cyclic structures through new carbon-carbon bonds.