enhanced permeation and retention (epr) effect

What is the Enhanced Permeation and Retention (EPR) Effect?

The Enhanced Permeation and Retention (EPR) effect is a phenomenon that allows nanoparticles and macromolecules to accumulate more efficiently in tumor tissue than in normal tissues. This effect is primarily due to the unique characteristics of the tumor microenvironment, such as abnormal vasculature and poor lymphatic drainage.

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