What is the Enhanced Permeability and Retention (EPR) Effect?
The Enhanced Permeability and Retention (EPR) effect is a unique phenomenon observed in solid tumors, which allows nanoparticles to preferentially accumulate in tumor tissue. This effect is due to the leaky nature of the tumor vasculature and poor lymphatic drainage. The EPR effect is crucial for the design and application of nanomedicine, enabling targeted delivery of therapeutic agents to cancer cells.
